Set in the waning years of the Old West, Dry River unfolds in a Mexican border town suffering from crippling drought. The town's only water supply is under the control of a ruthless American renegade family, intent on uncovering a fabled treasure. Tensions escalate when a Mexican man arrives to reclaim his father’s property, igniting a fierce conflict that irrevocably alters the fates of everyone involved. As desperation mounts, the clash between greed and heritage leads to explosive consequences, forever changing the landscape of their lives.