Dexter Riley, a science student at Medfield College, stumbles upon a remarkable formula that makes objects and people invisible. Eager to explore their groundbreaking find, Dexter and his friends, Debbie and Richard Schuyler, soon find themselves in a comical battle against the unscrupulous businessman A.J. Arno, who seeks to exploit the invisibility for his own nefarious purposes. As the trio navigates a series of hilarious misadventures, they must devise a plan to stop Arno from using the invention to execute a bank heist, all while enjoying the chaotic fun of their extraordinary creation.